Images: What Does DRESS Look Like DRESS Syndrome DRESS is an unexpected, severe reaction to medication. Several organs are commonly affected including the skin, liver, kidneys, lungs and heart. Not all of these organs may be affected at any one DRESS Syndrome: What Is It, Symptoms, Diagnosis, and More Osmosis DRESS Syndrome Rare Acute Dermatologic Emergency Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Pediatric EM Morsels